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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Hepatology. 2014 Jul 25;60(3):964–976. doi: 10.1002/hep.27082

Figure 5. Ablation of Wls in liver epithelial cells has no effect on hepatic zonation or initiation of LR.

Figure 5

A. IHC for GS, Cyp1a2 and Cyp2e1 in Con and Wls-LKO shows normal pericentral localization in both groups. (100×)

B. PCNA IHC shows comparable numbers of PCNA-positive hepatocytes in Con and Wls-LKO livers at 40 hours after PH (200×).

C. Quantification of PCNA staining confirms similar numbers of PCNA-positive hepatocytes in Con and Wls-LKO at 40 hours after PH.

D. Representative WB shows comparable Cyclin-D1 expression at 40 hours after PH in both Con and Wls-LKO livers.