Table 2.
Comparison of cardiorespiratory responses to CPET and 6MWT
| |
All (n =47) |
IPF Subgroup (n = 27) |
Non-IPF Subgroup (n = 20) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| CPET | 6MWT | p value | CPET | 6MWT | p value | CPET | 6MWT | p value | |
| VO2peak, L.min−1 |
1.25 (0.37) |
1.16 (0.27) |
0.006 |
1.19 (0.25) |
1.15 (0.23) |
0.20 |
1.46 (0.46) |
1.22 (0.33) |
0.002 |
| VCO2peak, L.min−1 |
1.38 (0.43) |
1.05 (0.30) |
<0.001 |
1.36 (0.37) |
1.05 (0.25) |
<0.001 |
1.53 (0.52) |
1.12 (0.34) |
<0.001 |
| VEpeak, L.min−1 |
55.5(16.6) |
42.8 (14.2) |
<0.001 |
56.8 (14.6) |
47.2 (17.1) |
<0.001 |
56.9 (20.6) |
36.8 (12.1) |
<0.001 |
| HRpeak, bpm |
127 (20.1) |
118 (14.8) |
0.001 |
126.1 (19.1) |
118.3 (16.3) |
0.009 |
128.6 (21.9) |
118.5 (13.0) |
0.03 |
| NadirSpO2, % |
89.3 (4.7) |
86.5 (6.2) |
<0.001 |
88.7 (5.4) |
85.3 (6.2) |
<0.001 |
90.2 (3.9) |
88.1 (6.1) |
0.07 |
| Borg dyspnoea score |
4.8 (1.6) |
3.7 (1.3) |
<0.001 |
5.1 (1.8) |
4.0 (1.6) |
0.006 |
4.6 (1.3) |
3.5 (1.1) |
<0.001 |
| Borg fatigue score | 4.1 (2.3) | 3.0 (1.9) | 0.001 | 3.9 (2.4) | 2.5 (1.3) | 0.004 | 4.4 (2.4) | 3.7 (2.5) | 0.13 |
Results are expressed as mean(SD). CPET = cardiopulmonary exercise test, 6MWT = six-minute walk test, VO2peak = peak oxygen uptake, VCO2peak = peak carbon dioxide production, VEpeak = peak minute ventilation, HRpeak = peak heart rate, NadirSpO2 = lowest oxyhaemoglobin saturation. p values are for comparison between tests.