Table 3.
|
All cohort (n =47) |
IPF subgroup (n = 27) |
Non-IPF subgroup (n = 20) |
||||||
---|---|---|---|---|---|---|---|---|---|
6MWD, meters | 6MWT VO 2 peak, L.min −1 | 6MWT Nadir SpO 2 | 6MWD, meters | 6MWT VO 2 peak, L.min −1 | 6MWT Nadir SpO 2 | 6MWD, meters | 6MWT VO 2 peak, L.min −1 | 6MWT Nadir SpO 2 | |
CPET VO2peak, L.min−1 |
0.71** |
0.71** |
0.28 |
0.74** |
0.79** |
0.24 |
0.55* |
0.77** |
0.35 |
CPET VCO2peak, L.min−1 |
0.77** |
0.74** |
0.19 |
0.77** |
0.78** |
0.14 |
0.69** |
0.80** |
0.35 |
CPET VEpeak, L.min−1 |
0.36* |
0.21 |
−0.03 |
0.31 |
0.24 |
−0.37 |
0.46* |
0.71** |
0.29 |
CPET Peak Work, Watts |
0.77** |
0.38* |
0.35* |
0.86** |
0.64** |
0.15 |
0.73** |
0.62** |
0.48* |
CPET NadirSpO2, % |
0.21 |
0.13 |
0.76** |
0.25 |
0.29 |
0.85** |
0.05 |
0.03 |
0.61** |
Age, years |
−0.42** |
−0.14 |
−0.23 |
−0.42* |
−0.41* |
0.04 |
−0.47* |
−0.09 |
−0.35 |
Height, cm |
0.09 |
−0.20 |
0.10 |
0.10 |
0.06 |
−0.15 |
0.15 |
0.51* |
0.35 |
FVC%pred |
0.22 |
−0.12 |
0.50** |
0.13 |
0.04 |
0.49* |
0.37 |
0.04 |
0.52* |
TLCO%pred |
0.34* |
0.14 |
0.60** |
0.28 |
0.35 |
0.64** |
0.39 |
0.27 |
0.47* |
RVSP, mmHg | −0.46* | −0.33 | −0.48 | −0.49 | −0.43 | −0.47 | −0.16 | 0.37 | 0.73 |
Data are Pearson’s r. *p <0.05, **p < 0.01 for relationship between variables. CPET = cardiopulmonary exercise test, VO2peak = peak oxygen uptake, 6MWT = six-minute walk test, 6MWD = six-minute walk distance, NadirSpO2 = lowest oxyhaemoglobin saturation, VO2 – oxygen uptake, VCO2 - carbon dioxide production, VE – ventilation, FVC – forced vital capacity, TLCO – diffusing capacity for carbon monoxide, RVSP – right ventricular systolic pressure on trans-thoracic echocardiogram.