Fig. 1.

Effects of one-day exposure to amodiaquine (AQ) and praziquantel (PZQ) on daily egg output of Schistosoma mansoni adult worm pairs. (a) Paired adult worms were incubated for one day with zero for control (closed circle), 1 (closed square), 2 (closed diamond), 5 (closed triangle), or 10 (cross) μg/ml AQ, or (b) with zero for control (closed circle), 0.01 (closed square) 0.02 (closed diamond), 0.05 (closed triangle), or 0.1 (cross) μg/ml PZQ, and subsequently incubated with daily replacement of media on the other days. Each bar shows the arithmetic mean ± standard error of daily egg output. *P < 0.01, **P < 0.05, compared with the corresponding control group by the Mann-Whitney test. †one day pre-incubation before worms were exposed to the drugs.