Table 2.
Adjuvant chemotherapy (cycles), n = 231 | n | % |
---|---|---|
With docetaxel | 157 | 68 |
TAC × 6 | 46 | 20 |
ET × 4 → X × 4 | 39 | 17 |
EC × 4 → T × 4 | 39 | 17 |
AT × 4 → CMF × 4 | 21 | 9 |
A × 3 → T × 3 → CMF × 3 | 12 | 5 |
With paclitaxel | 74 | 32 |
FAC × 4 → T × 8 | 48 | 21 |
AT × 4 → CMF × 3 | 13 | 5 |
FEC × 4 → T × 8 | 11 | 5 |
AC × 4 → T × 8 or T × 12 | 2 | 1 |
Chemotherapy administration, n = 231 | n | % |
---|---|---|
Delayed cycles | ||
<2 cycles | 216 | 94 |
≥2 cycles | 15 | 6 |
Delayed days | ||
<15 days | 226 | 98 |
≥15 days | 5 | 2 |
Relative dose intensity | ||
≥85 % | 226 | 98 |
<85 % | 5 | 2 |
Prophylaxis with G-CSF, n = 231 | n | % |
---|---|---|
Yes | 84 | 36 |
Primary prophylaxis | 55 | 24 |
Secondary prophylaxis | 29 | 12 |
No | 147 | 64 |
G-CSF given later to treat neutropenia | 8 | 3 |
A doxorubicin, C cyclophosphamide, E epirubicin, F 5-fluorouracil, G-CSF granulocyte colony-stimulating factor, M methotrexate, T taxane (docetaxel or paclitaxel), X capecitabine