Table 2.

Multivariate OR for discontinuation of ACE inhibitors subsequent to elevation of SCr post-ACEI initiation

Co morbidities	Multivariate OR (95% CI)	p Value
Age	1.00 (1.00 to 1.00)*	0.452
Gender (male)	0.74 (0.57 to 0.97)	0.028
Coronary artery disease	0.89 (0.79 to 1.01)	0.061
Chronic heart failure	0.79 (0.63 to 0.99)	0.041
SBP <100 mm Hg	0.55 (0.40 to 0.76)	<0.001
Concomitant use of:
NSAIDs	1.23 (1.13 to 1.34)	<0.001
Diuretics	1.07 (0.87 to 1.31)	<0.001
Thiazides	1.18 (0.98 to 1.42)	0.084
Loops	0.99 (0.84 to 1.18)	0.925
β-blockers	1.17 (1.08 to 1.27)	<0.001

*Values rounded from 0.999 (0.995 to 1.002).

NSAIDs, non-steroidal anti-inflammatory drugs; SBH, systolic blood pressure.