Table 3.
Distribution in magnitude of elevation of serum creatinine in patients who discontinued ACE inhibitors within 90 days post-initiation
| Threshold of increase in SCr | Group 1* <1.5 mg/dL n=135 |
Group 2* 1.5–2 mg/dL n=28 |
Group 3* >2 mg/dL n=19 |
p Value |
|---|---|---|---|---|
| ≤0.5 mg/dL increase | 124 (91.85) 0.17±0.11; 0.10 |
25 (89.29) 0.18±0.8; 0.17 |
8 (42.10) 0.27±0.14; 0.3 |
<0.001 |
| >0.5 mg/dL increase | 11 (8.15) 1.23±0.99; 0.80 |
3 (10.71) 0.87±0.25; 0.9 |
11 (57.90) 2.95±2.93; 1.7 |
<0.001 |
| ≤30% increase | 114 (84.45) 14.15%±6.85%; 11.11% |
25 (89.29) 10.22%±4.6%; 9.25% |
12 (63.15) 12.82%±6.64%; 12.99% |
0.01 |
| >30% increase | 21 (15.55) 89.25%±81.07%; 46.67% |
3 (10.71) 45.83%±8.78%; 45% |
7 (36.85) 100.32%±69.10%; 88.23% |
<0.001 |
*Values are n (%) and mean±SD; median.