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Clinically approved contrast agents: GdIII-containing diethylenetriaminepentaacetate (DTPA), 1; GdIII-containing 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (DOTA), 2; GdIII-containing α-(benzyloxymethyl)diethylenetriaminepenta-acetate (BOPTA), 3; GdIII-DOTA derivative 4; and GdIII-DTPA derivatives 5 and 6 (coordinated water molecules and counter ions are not shown for clarity).
