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Schematic of aggrecan aggregate. Arrow indicates large aggrecan aggregate with an enlarged area depicting aggrecan molecules consisting of a core protein, keratan and chondroitin sulfate GAGs linked via the G1 globular domain to the hyaluronic acid monomer. Modified from Fox AJS, Bedi A, Rodeo SA. The basic science of human knee menisci: structure, composition, and function. Sports Health: A Multidisciplinary Approach. 2012; 4: 340. DOI: 10.1177/1941738111429419
