Table 1.
Baseline characteristics of patients with SDF-1 AA/AG or GG genotype.
| Variable | SDF-1 | ||
|---|---|---|---|
| AA/AG | GG | p | |
| Number | 121 | 131 | |
| Adverse outcome (n, %) | 16 (13.2) | 9 (6.9) | 0.092 |
| Gender (male, %) | 57 (47.1) | 69 (52.7) | 0.377 |
| Age at transplant (year) | 53.0 ± 10.5 | 51.8 ± 12.3 | 0.559 |
| HLA mismatch (n, %) | |||
| ≤3 | 71 (65.7) | 73 (61.3) | 0.492 |
| >3 | 37 (34.3) | 46 (38.7) | |
| Parental DM (n, %) | 10 (8.3) | 13 (9.9) | 0.648 |
| Cigarette smoke (n, %) | 31 (26.1) | 39 (30.5) | 0.441 |
| HBV (n, %) | 13 (10.7) | 11 (8.4) | 0.526 |
| HCV (n, %) | 14 (11.6) | 7 (5.3) | 0.074 |
| Hypertension (n, %) | 98 (81) | 106 (80.9) | 0.988 |
| Cardiovascular event (n , %) | 6 (5) | 7 (5.3) | 0.890 |
| CVA | 3 (2.5) | 2 (1.5) | 0.588 |
| CAD | 2 (1.7) | 2 (1.5) | 0.936 |
| PAOD | 2 (1.7) | 4 (3.1) | 0.466 |
| Blood chemistry at Tx | |||
| Glucose (g/dL) | 95.6 ± 11.7 | 97.3 ± 12.4 | 0.494 |
| Triglyceride (mg/dL) | 123.6 ± 52.2 | 142.9 ± 77.7 | 0.187 |
| Total cholesterol (mg/dL) | 164.6 ± 35.9 | 163.6 ± 35.6 | 0.869 |
| Albumin (g/dL) | 4.2 ± 0.56 | 4.2 ± 0.48 | 0.862 |
| Calcium (mg/dL) | 9.0 ± 1.03 | 9.0 ± 1.05 | 0.890 |
| Phosphate (mg/dL) | 2.49 ± 1.39 | 2.54 ± 1.35 | 0.839 |
| Body mass index (kg/m2) | 22.0 ± 3.3 | 22.6 ± 3.6 | 0.183 |
| Treatment (n, %) | |||
| Tacrolimus | 92 (76) | 100 (76.3) | 0.626 |
| Cyclosporine | 28 (23.1) | 28 (21.4) | |
| Serum Creatinine post-Tx | |||
| 1 month | 1.47 ± 1.02 | 1.45 ± 0.79 | 0.788 |
| 3 month | 1.32 ± 0.38 | 0.33 ± 0.38 | 0.720 |
| 6 month | 1.29 ± 0.43 | 1.32 ± 0.40 | 0.232 |
| 12 month | 1.26 ± 0.48 | 1.28 ± 0.50 | 0.988 |
| Δ12-6 | −0.04 ± 0.36 | −0.04 ± 0.34 | 0.707 |
Abbreviation: HLA, human leukocyte antigen; DM, diabetes mellitus; CVA, cerobrovascular accident; CAD, cardiovascular disease; PAOD, peripheral arterial occlusive disease.