Table 2.
The genotype and allele frequency of the promoter gene of FcεR1α (FcεR1α –66T>C, rs2251746 and –334C>T, rs242782).
| Loci and Genotype | AICU (n = 20) | Normal Controls (NC) (n = 50) | Airway Allergies (AA) (n = 52) | * p Value | |
|---|---|---|---|---|---|
| AICU vs. NC | AICU vs. AA | ||||
| FcεR1α –66T>C | |||||
| TT | 19 (95.0%) | 38 (76.0%) | 42 (80.8%) | ||
| TC | 1 (5.0%) | 12 (24.0%) | 10 (19.2%) | 0.091 | 0.27 |
| † H-W-P | <0.001 | 0.864 | 0.724 | ||
| FcεR1α –344C>T | |||||
| CC | 20 (100%) | 40 (80%) | 36 (69.2%) | 0.097 | 0.019 |
| CT | 0 (0.0%) | 9 (18%) | 9 (17.3%) | ||
| TT | 0 (0.0%) | 1 (2%) | 7 (13.5%) | ||
| † H-W-P | <0.001 | 0.850 | 0.002 | ||
* by the chi-square test; † H-W-P, p value for the Hardy–Weinberg equilibrium patients in question.