Skip to main content
. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Lancet Oncol. 2013 Sep;14(10):e425–e435. doi: 10.1016/S1470-2045(13)70128-1

Table 1.

Agent Target (IC50)
AMG900 Aurora A (5 nM)
Aurora B (4 nM)
Aurora C (1nM)
MLN8237 Aurora A (61 nM)
AZD1152 Aurora A (1369 nM)
Aurora B (.36 nM)
Aurora C (17 nM)
PHA-739358 Aurora A (13 nM)
Aurora B (79 nM0
Aurora C (61 nM)
Tozasertib Aurora A (0.6 nM)
Aurora B (18 nM)
Aurora C (4.5 nM)
AT9283 Aurora A (3 nM)
Aurora B (3 nM)
ENMD2076 Aurora A (13 nM)
Aurora B (350 nM)