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. Author manuscript; available in PMC: 2014 Aug 21.
Published in final edited form as: Am J Surg Pathol. 2011 Sep;35(9):1311–1326. doi: 10.1097/PAS.0b013e31821ec4ce

TABLE 4.

Adrenocortical Pathologic Findings*

Adrenal Weight, g
Microscopic Pathology
Patient Right Left Gross Pathology Cortical
Nodules
Cortical
Hyperplasia
Cortical
Atrophy
Fetal
Cortex
1 4.2 4.7 Slightly nodular, hyperplastic dark green parenchyma Yes Acidophilic; cortex up to 1 mm thick Yes Present
2 NA NA NA No Acidophilic Yes Present
3 NA NA Cortex thickened; yellow nodules, with darker center, some extra-adrenal Yes Clear cell >acidophilic Yes Absent
4 9.5 NA Marked increase in cortical tissue Absent. Adenoma bilaterally Acidophilic No Absent
5 3.5 4.0 Smooth outline preserved; cut surface reddish-brown with alternating tan-to-green nodules Yes, vague Acidophilic; cortex up to 1.2 mm thick Yes Present
6 3 3.2 NA Yes Acidophilic Yes Present. Cytomegaly and cortical cysts
7 1.5 2.0 R: Tan nodule, 4 × 2 × 2 cm Yes Clear cell >Acidophilic Yes
8 1.8 2.0 Small yellow nodules, 2–3.5 mm. Residual cortex brown Yes Acidophilic Yes Present
9 4 Not resected Yellow-gray cortex 0.05 cm thick Yes Acidophilic with cortex up to 0.6 mm thick Yes Present
10 2.6 2.3 Cortices slightly thickened Yes Clear and acidophilic Yes Absent
*

Patients 1 through 9 had Cushing syndrome and McCune-Albright syndrome. Patient 10 had Cushing syndrome, but not McCune-Albright syndrome.

Prominent accumulations of zona glomerulosa-type cells around periphery of gland.

NA indicates not available; R, right.