TABLE 5.

Adrenocortical Immunocytochemical Findings^*

	Vimentin		Synaptophysin		Inhibin-A		Melan A		CD56		MIB-1
Patient	Hyperplasia and Nodules	Atrophy	Hyperplasia and Nodules	Atrophy	Hyperplasia and Nodules	Atropy	Hyperplasia and Nodules	Atropy	Hyperplasia and Nodules	Atrophy	Hyperplasia and Nodules	Atropy
1	3+, outer cortex, fine gran	Neg	2+, cyto body	Neg	3+, fine gran	Superficial : neg. Deep: 1+	3+, coarse gran	Neg to 1+, fine gran	Neg	1+, cell membrane, fine gran	Occ stained nuclei	Many stained nuclei
2	3+, fine gran	Neg	3+, large cyto body	1+, outer	3+2 2+, coarse grain	1+, deep, cell membrane	3+, fine gran	1+, fine gran	1+, patchy, cell membrane	3+, cell membrane	Occ stained nuclei	Occ stained nuclei
3	3+, patchy, cell membrane and cyto body, fine gran	Occ cells +	3+, patchy, fine gran, cell membrane and cyto body	Neg	3+ to 2+, coarse gran	Neg	3+, coarse bran	2+ to 1+, fine gran	1+, cell membrane, patchy to neg	3+, cell membrane	1+	2+ to neg
5	Neg	Neg	3+, fine gran, cell membrane and cyto body	Neg to 1+	3+ to 2+, fine and coarse gran	Neg to 1+	2+ to 1+, patchy, fine and coarse gran	Neg	1+, subcapsular	2+, cell membrane, coarse gran, focal	NA	NA
8	3+, patchy, fine and coarse gran	Neg	3+, cell membrane and cyto body, fine gran	Neg	3+ to +2, coarse gran	Neg	1+, fine gran	Neg	Neg	3+, cell membrane, cyto, fine gran	1+	1+
10	3+, coarse gran	Neg	1+, cell membrane and cyto body, fine gran	Neg	3+, coarse gran	Neg	3+ to 2+, coarse gran	Neg	Neg	3+, cell membrane, fine gran	1+	1+

^*Cyto indicates cytoplasmic; gran, granularity; NA, not available; occ, occasional.

Patients 1,2, 3, 5, and 8 had Cushing syndrome and McCune-Albright syndrome. Patient 10 had Cushing syndrome but not McCune-Albright syndrome.

Staining, negative 3+, heavy ; 2+, moderate; 1+, light.