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. Author manuscript; available in PMC: 2014 Aug 21.
Published in final edited form as: Dig Dis Sci. 2010 Oct 9;56(5):1342–1353. doi: 10.1007/s10620-010-1421-0

Fig. 2.

Fig. 2

Epithelial cell barrier function after treatment with S1P. A Paracellular permeability. Dose response of cells exposed to S1P for 4 h. B Time course response to S1P (0.5 μM). (C) TEER data for conditions replicating A (i) and B (ii). Values are means ± SE of data from six samples. * P <0.05 compared with control IECs unexposed to S1P. D Paracellular permeability comparing S1P (0.5 μM) with co-incubation of cycloheximide (CHX—25 μg/ml) alone and CHX + S1P. * P <0.05 compared with control IECs unexposed to S1P. The results shown are means from six experiments. All cells were viable (early passage) at the time of experimentation