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. Author manuscript; available in PMC: 2014 Aug 21.
Published in final edited form as: Arch Virol Suppl. 1994;9:531–541. doi: 10.1007/978-3-7091-9326-6_51

Fig. 3.

Fig. 3

Top: View of the icosahedral asymmetric unit bounded by adjacent five- and threefold axes, outlining residues on the viral surface. Shown are the limits of the canyon, arbitrarily demarcated by a 138 Å radial distance from the viral center [28], and the ICAM-1 footprint (stippled). Improved resolution of the electron density could only marginally alter the HRV residues at the virus:receptor interface. Left and right: Enlarged view of the residues in the ICAM-1 footprint showing (right) the residues which, when mutated, affect viral attachment [5], and (left) the residues altered in structure by the binding of antiviral compounds that inhibit attachment and uncoating [32]