Table 1.

Effects of WPC on body weight and urine parameters.

	Body weight (g)		Urine volume (mL/kg/day)		Uosmol (osmol/kg)
	Start	Final	Start	Final	Start	Final
Sham	195.58 ± 0.55	239.84 ± 4.87	27.83 ± 3.51	32.45 ± 3.64	5.38 ± 426.79	6.94 ± 623.57
PAN	195.92 ± 2.64	228.04 ± 5.22	35.52 ± 5.46	68.72 ± 19.00∗∗	7.42 ± 754.30	2.84 ± 1630.36∗∗
Losartan	201.62 ± 2.82	220.24 ± 4.21	29.42 ± 5.72	53.60 ± 9.97∗∗	6.83 ± 1376.62	2.30± 783.01∗∗
WPC	201.60 ± 1.77	230.18 ± 5.21	27.57 ± 4.66	56.95 ± 12.37∗∗	7.05 ± 1249.11	2.28 ± 994.74∗∗
	UNa+ (meq/24 h/kg)		UK+ (meq/24 h/kg)		UCl− (meq/24 h/kg)
	Start	Final	Start	Final	Start	Final
Sham	2.39 ± 102.84	2.15 ± 185.92	11.06 ± 989.83	13.48 ± 881.46	1.08 ± 1062.77	13.60 ± 967.50
PAN	2.17± 199.89	0.88 ± 135.24∗∗	12.38 ± 1198.84	10.52 ± 852.33∗	13.32 ± 1201.95	9.03 ± 2298.03∗∗
Losartan	2.48 ± 184.68	0.75 ± 133.15∗∗	10.83 ± 1239.06	9.55 ± 1347.23∗	12.30 ± 1844.92	8.39 ± 1719.22∗∗
WPC	2.58 ± 42.72	0.836 ± 81.45∗∗	10.74 ± 799.05	11.03 ± 452.83∗	12.73 ± 1109.83	9.64 ± 1448.94∗∗

Values are expressed as mean ± S.E. (n = 5); *P < 0.05, **P < 0.001 versus sham group.