Table 3.

Association of haplotypes in the MTHFR gene with risk of T2DM.

Haplotype∗	Cases, %	Controls, %	OR† (95% CI)	OR (95% CI)‡
CTTTGA	34.9	32.2	1.00	1.00
CTCCGA	26.9	35.3	0.73 (0.60–0.88)	0.71 (0.58–0.87)
ATTCGC	17.3	12.5	1.22 (0.95–1.56)	1.20 (0.92–1.55)
ACTCAC	8.6	8.2	0.92 (0.67–1.25)	0.93 (0.67–1.29)
CTTCGA	6.7	8.8	0.79 (0.57–1.10)	0.80 (0.56–1.13)

*In the order rs12121543, rs13306553, rs9651118, rs1801133, rs2274976, and rs1801131.

^†Adjusted for age. ^‡Adjusted for age, sex, BMI, and hypertension.