Table 1.
Components of the Framingham score by group
| Components | Diabetes | Prediabetes | NGR | P value |
|---|---|---|---|---|
| DPP baseline | ||||
| Age (years) | 50.9 (10.4) | 52.4 (10.4) | 50.7 (10.4) | 0.015 |
| Female (%) | 66.5 | 70.4 | 67.2 | 0.34 |
| TC (mg/dL) | 203 (35) | 206 (37) | 203 (36) | 0.38 |
| HDL (mg/dL) | 44 (11) | 46 (12) | 46 (12) | <0.001 |
| SBP (mmHg) | 125 (15) | 125 (15) | 123 (14) | <0.001 |
| Use of antihypertensive medications (%) | 20 | 18 | 14 | <0.001 |
| Current smoker (%) | 8.7 | 7.1 | 5.4 | 0.009 |
| DPPOS baseline | ||||
| Age (years) | 56.2 (10.3) | 57.4 (10.3) | 55.9 (10.3) | 0.025 |
| Female (%) | 66.5 | 70.4 | 67.2 | 0.34 |
| TC (mg/dL) | 191 (35) | 199 (51) | 195 (36) | <0.001 |
| HDL (mg/dL) | 45 (12) | 47 (13) | 49 (13) | <0.001 |
| SBP (mmHg) | 125 (15) | 124 (15) | 121 (14) | <0.001 |
| Use of antihypertensive medications (%) | 49 | 40 | 30 | <0.001 |
| Current smoker (%) | 6.8 | 7.1 | 5.8 | 0.49 |
Data are presented as mean (SEM) for age, TC, HDL, and SBP and percentage for the female, use of antihypertensive medications, and current smoker categories.
Data from DPP baseline were collected on or before randomization, while data from DPPOS baseline reflect the first assessment in the DPPOS (e.g., DPPOS year 1).