Figure 1.

Subject characteristics over the 6-month study period. Means ± SE of weight, fasting capillary glucose as determined by glucometer readings, and HbA_1c in each group. Also shown for the glimepiride group is the average dose at each monthly visit. Changes in weight over time were not significantly different across the three groups [F(12, 222) = 1.1013; P = 0.4]. Average capillary glucose was significantly different [F(12, 204) = 2.53; P < 0.01] when comparing across all three groups. HbA_1c was different by trend [F(4, 74) = 2.28; P < 0.1] when comparing across all three groups. *P < 0.05 when comparing Δ from baseline within each group at each time point.