Table 1.

NA and DA activate PKA across cortical region and layers.

		Frontal		Parietal		Occipital
Drugs (n/N)	Layer	Amplitude (% FSK)	T10–90% (s)	Amplitude (% FSK)	T10–90% (s)	Amplitude (% FSK)	T10–90% (s)
DA	II/III	32.5 ± 3.3 (39/3)	109.9 ± 14.1 (22/3)	49.5 ± 1.8 (242/12)	110.5 ± 4.8 (181/12)	46.4 ± 3.9 (38/2)	61.7 ± 7.1 (27/2)
	V	28.5 ± 2.4 (44/3)	170.0 ± 13.1 (30/3)	33.7 ± 3.1 (105/6)	143.4 ± 11.9 (53/6)	44.1 ± 3.8 (37/3)	119.3 ± 14.0 (37/3)
NA	II/III	74.5 ± 3.7 (37/2)	57.8 ± 3.0 (32/2)	61.9 ± 2.9 (114/7)	74.3 ± 2.0 (84/7)	61.3 ± 2.5 (77/2)	53.3 ± 2.8 (62/2)
	V	57.6 ± 3.5 (26/3)	90.2 ± 4.9 (21/3)	72.5 ± 5.0 (29/2)	48.8 ± 2.8 (26/2)	53.9 ± 3.5 (43/4)	68.4 ± 3.2 (35/4)
SKF	II/III	21.1 ± 3.4 (31/4)	147.4 ± 9.9 (39/4)	19.9 ± 1.4 (196/10)	134.9 ± 7.9 (81/10)	34.5 ± 2.6 (40/4)	55.2 ± 3.4 (31/3)
	V	22.0 ± 3.6 (36/4)	192.4 ± 20.2 (24/3)	31.4 ± 3.8 (60/4)	106.3 ± 8.9 (32/4)	32.9 ± 2.8 (69/5)	64.6 ± 5.9 (28/3)
ISO	II/III	55.8 ± 2.0 (76/4)	69.2 ± 3.5 (70/4)	48.1 ± 1.5 (172/7)	45.7 ± 1.2 (98/7)	52.3 ± 3.1 (40/3)	47.5 ± 2.5 (32/3)
	V	43.5 ± 2.5 (50/4)	54.0 ± 3.8 (46/4)	48.9 ± 3.8 (60/4)	65.9 ± 4.1 (47/4)	46.8 ± 2.1 (135/5)	62.7 ± 4.3 (50/5)