FIGURE 11.

Comparison of interactions between Tth UDGb-N120 with water and E. coli MUG-N18 with water. A, superimposition of UDGb-AP structure (Protein Data Bank code 2DEM; green) with E. coli MUG structure (Protein Data Bank code 1MUG; silver). The AP site is colored by atom type. The two structures were superimposed using the program VMD. B, close-up view of Tth UDGb-N120-water and E. coli MUG-N18-water interactions using the same coloring scheme described in A. Asn¹²⁰ and the interacting water in Tth UDGb structure are shown in purple. Asn¹⁸ and the interacting water in the MUG structure are shown in orange.