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C. difficile toxins and toxin fragments. A, domain structures of TcdA and TcdB showing the putative receptor binding (CROP) domains at the C terminus. B, TcdB CROP domain showing SRs (green) and LRs (gray) and highlighting the four peptides used in this study, B1, B2, B3, and B4. The first of four CROP units, consisting of one LR flanked by three SRs on the N-terminal side and two SRs on the C-terminal side, is highlighted in red.
