Alignment of NHE3 sequences.
A, alignment of partial NHE3 sequences from 25 species is shown. PY motifs are enclosed by a square. The numbers indicate the positions of the amino acid residues. B, a phylogenetic tree of primates is shown. 1, Prosimians; 2, New World monkeys; 3, Old World monkeys; 4, Hominoidea; 5, Hominidae.