Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
EM images of various conformational states of insulin. A, fibrils at pH 2.0 with no alcohol. B, amorphous aggregates at pH 4.8 with no alcohol. C and G, fibrils at pH 2.0 and 20% TFE. D and H, fibrils at pH 4.8 and 20% TFE. E and I, fibrils at pH 2.0 and 10% HFIP. F and J, fibrils at pH 4.8 and 10% HFIP. Insulin fibrils were prepared by ultrasonication (A–F) or seeding (G–J). The black bars indicate 1 μm.
