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TRPC3 channels are not involved in TNFα-induced sustained intracellular Ca2+ elevation in rodent microglial cells. A and B, an average trace showing the effect of the 3 μm Pyr3 after the onset of 50 units/ml IFN-γ-induced or 2 μg/ml TNFα-induced sustained elevation of [Ca2+]i in primary rat microglial cells. Each panel demonstrates the average trace determined from 10 representative traces of [Ca2+]i in each condition.
