Table 3. Direct C–H Vinylation: Vinyl Sulfone Scopea.
All reactions performed using the conditions described in Table 2. Yields are of isolated products. E:Z ratio determined by 1H NMR analysis.
Isomerization from 82:18 E:Z (crude ratio) to >98:2 E:Z occurred during the mildly acidic purification conditions. NPhth = phthalimidoyl.