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. Author manuscript; available in PMC: 2014 Aug 21.
Published in final edited form as: Biochem Biophys Res Commun. 2005 Nov 17;339(2):597–602. doi: 10.1016/j.bbrc.2005.11.051

Table 1.

Kinetic and affinity data of the interaction of ATIII with N-sulfoheparosan-C5-epi, 2-OST, 6-OST, 3-OST, and HP

Kona (×106 M−1 s−1) Koffa (×10−2 s−1) K+1b (×10−3 s−1) K−1b (×10−3 s−1) KD (nM) χ2
ATIII with N-sulfoheparosan-C5-epi, 2-OST, 6-OST, 3-OST 0.67 ± 0.01 0.62 ± 0.02 7.10 ± 0.11 3.61 ± 0.04 61.7 2.67
ATIII with HP 21.6 ± 0.03 3.63 ± 0.06 5.81 ± 0.10 2.85 ± 0.05 8.5 29.70
a

Kon,Koff: on and off rate constants of the binding step.

b

K+1,K−1: on and off rate constants of the conformational change.