Table 1.
Kona (×106 M−1 s−1) | Koffa (×10−2 s−1) | K+1b (×10−3 s−1) | K−1b (×10−3 s−1) | KD (nM) | χ2 | |
---|---|---|---|---|---|---|
ATIII with N-sulfoheparosan-C5-epi, 2-OST, 6-OST, 3-OST | 0.67 ± 0.01 | 0.62 ± 0.02 | 7.10 ± 0.11 | 3.61 ± 0.04 | 61.7 | 2.67 |
ATIII with HP | 21.6 ± 0.03 | 3.63 ± 0.06 | 5.81 ± 0.10 | 2.85 ± 0.05 | 8.5 | 29.70 |
Kon,Koff: on and off rate constants of the binding step.
K+1,K−1: on and off rate constants of the conformational change.