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. 2014 Aug 21;10(8):e1004513. doi: 10.1371/journal.pgen.1004513

Figure 5. lin-3, lin-1 and the LET-60-MPK-1 pathway act in the same pathway to promote PCD.

Figure 5

(A) The percentage of worms with surviving ABpl/rpppapp of the indicated genotypes was shown. *indicates P<0.05 when compared to the wild-type (Fisher's exact test). ns indicates no statistical difference (p>0.05). More than thirty worms were scored for each genotype. (B) Analysis of extra surviving cells in the pharyngeal region (n = 20). Alleles used here are let-60(sy93), mpk-1(ku1), lin-1(sy254), and lin-31(n301). (C) The percentage of wild-type or egl-1(n1084n3082) worms carrying the indicated transgene that lost gland cell(s) in the pharynx was shown. **P<0.001 (Fisher's exact test). The gland cells were scored using the tpIs8 transgene, and the worms were treated with heat shock as described in Materials and Methods. Phsp::lin-1 or Phsp indicate the transgenes, in which lin-1 or no cDNA was expressed under the control of the heat-shock promoter, respectively. More than forty worms were scored for each genotype.