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. 2014 Aug 21;10(8):e1003782. doi: 10.1371/journal.pcbi.1003782

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© 2014 Chu, Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The free energy landscapes of rigid and flexible binding are plotted at the corresponding binding temperature . (B) The differences of kinetics, represented by the ratio of binding time between rigid and flexible binding, are plotted along the differences of intrinsic specificity between rigid and flexible binding.

Inline graphic — (A) The free energy landscapes of rigid and flexible binding are plotted at the corresponding binding temperature . (B) The differences of kinetics, represented by the ratio of binding time between rigid and flexible binding, are plotted along the differences of intrinsic specificity between rigid and flexible binding.