Table 4.
Main effects analysis of timepoint (week 6 vs. week 12) for histological scoring and micro-CT morphometric parameters (p < 0.05).
| Histological scoring parameters | Micro-CT morphometric parameters | ||
|---|---|---|---|
| Overall Filling | 12wk > 6wk | Bone Mineral Density | 12wk > 6wk |
| Overall Degradation | 12wk > 6wk | Percent Bone Volume | 12wk > 6wk |
| Bone Filling | 12wk > 6wk | Intersection Surface | 12wk > 6wk |
| Bone Morphology | 12wk > 6wk | Bone Specific Surface | 6wk > 12wk |
| Bone Bonding | -- | Object Number | 6wk > 12wk |
| Cartilage Morphology | -- | ||
| Cartilage Thickness | 6wk > 12wk | ||
| Surface Regularity | -- | ||
| Chondrocyte Clustering | -- | ||
| Neocartilage GAG & Cell | 6wk > 12wk | ||
| Adjacent GAG & Cell | 12wk > 6wk | ||