Figure 4. Quantification of BLI data of OF-1 mice infected with luminescent T.b. brucei, T.b. rhodesiense and T.b. gambiense.

OF-1 mice (n = 3) were infected with T.b. brucei AnTaR 1 wild-type, T.b. brucei AnTaR 1 RLuc, T.b. brucei AnTaR 1 CBR, T.b. brucei AnTaR 1 P9, T.b. rhodesiense RUMPHI CBR, T.b. gambiense LiTaR 1 CBR and their luminescence was measured at 1, 4, 7, 18 and 26 post-infection in BLI using their respective substrates. The BLI data were divided in 3 ROIs; (A) abdomen, (B) thorax and (C) head and expressed as ph s⁻¹ cm⁻² sr⁻¹.