Figure 7. Visualisation of BLI data in untreated and CPA-treated OF-1 mice infected with T.b. gambiense.

OF-1 mice (n = 3) were infected with T.b. gambiense 348 BT RLuc without (A–E) or with CPA treatment (F–J) and their luminescence was measured with ViviRen or were infected with T.b. gambiense 348 BT CBR without (K–P) or with (Q–V) CPA treatment and their luminescence was measured with D-luciferin. Rows represent measurements at 1, 3, 7, 11, 43 (for RLuc) and 60 days post-infection (only CBR). In square P one mouse woke up from anesthesia just before the end of acquisition.