Table 4.
Variable | Lower Oxygen Saturation |
Higher Oxygen Saturation |
Adjusted Relative Risk (95% CI) |
P Value |
---|---|---|---|---|
number/total number (percent) | ||||
Strabismus | 46/478 (9.6) | 41/510 (8.0) | 1.20 (0.80–1.80) | 0.38 |
Nystagmus | 22/479 (4.6) | 13/510 (2.5) | 1.81 (0.89–3.69) | 0.10 |
Eyes track 180 degrees | 462/476 (97.1) | 493/507 (97.2) | 1.00 (0.98–1.02) | 0.93 |
Corrective lenses for both eyes† | 21/468 (4.5) | 20/493 (4.1) | 1.15 (0.63–2.10) | 0.65 |
Blind with some function in both eyes† | 3/450 (0.7) | 2/475 (0.4) | 1.57 (0.27–8.96) | 0.61 |
Blind with no useful vision in both eyes† | 2/449 (0.4) | 4/477 (0.8) | 0.54 (0.10–2.96) | 0.48 |
Other abnormal eye finding†‡ | 6/453 (1.3) | 12/485 (2.5) | 0.55 (0.21–1.46) | 0.23 |
Blind in at least one eye | 5/479 (1.0) | 8/511 (1.6) | 0.67 (0.22–2.02) | 0.48 |
Eye surgery performed§ | 31/477 (6.5) | 67/509 (13.2) | 0.53 (0.35–0.78) | 0.002 |
Relative risks and P values were adjusted for stratification factors (study center and gestational-age group) and familial clustering; analyses of blindness and other abnormal eye finding were not adjusted for study center, owing to the small numbers of patients with these characteristics.
The reference group for relative risk was the group of children with vision that appeared to be normal in both eyes.
Other abnormal eye finding was defined as an abnormality other than a condition requiring corrective lenses but not one severe enough for the child to be considered blind in that eye. Children whose eyes were classified in two different vision categories were included in the other-abnormal-eye-finding category.
Reasons for surgery are listed in Table S5 in the Supplementary Appendix.