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. 2014 Aug 21;9(8):e105252. doi: 10.1371/journal.pone.0105252

Table 1. Comparison of baseline characteristics of patients receiving low-dose aspirin and patients receiving high- dose aspirin*.

Characteristic Patients receiving low-dose aspirin (N = 273) Patients receiving high-dose aspirin (N = 97) P value
Age — yr 59.2±8.1 58.2±9.3 0.39
Male sex — no. (%) 228(83.5) 75 (77.3) 0.22
Risk factors— no. (%)
Hypertension 222 (81.3) 73 (75.3) 0.24
Hyperlipidemia 158 (57.9) 57 (58.8) 0.91
Diabetes mellitus 92 (33.7) 33 (34.0) 1.00
Smoking 164 (60.1) 47 (48.5) 0.07
Obesity 24 (8.8) 9 (9.3) 0.84
Qualifying ischaemic events — no. (%)
TIA 149 (54.6) 64 (66.0) 0.06
Stroke 124 (45.4) 33 (34.0) 0.06
Symptomatic qualifying artery — no. (%)
BA 109 (40.0) 38 (39.2) 1.00
Intracranial vertebral 101 (37.0) 35 (36.1) 0.90
MCA 34 (12.5) 15 (15.5) 0.49
Intracranial carotid 29 (10.6) 9 (9.3) 0.85
Cases with loading dose of clopidogrel 12 (4.4) 4 (4.1) 1.00
Time from qualifying event to endovascular treatment— days 0.52
Median 25 22
Interquartile range 10–41 12–30

*Plus–minus values are means ±SD. Baseline characteristics of the two groups were compared with the use of either an independent groups t-test (for means) or a chi-square test (for percentages). TIA denotes transient ischaemic attack; BA denotes basilar artery; MCA denotes middle cerebral artery.