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. 2014 Aug 21;8(8):e3091. doi: 10.1371/journal.pntd.0003091

Figure 5. Anti-leishmanial activity of macrophages from liposomal CP immunized hamsters.

Figure 5

A, Percentages of infected peritoneal MΦs from different groups of hamsters from different liposomal CP immunized groups after infection with L. donovani promastigotes. B, Total number of amastigotes/1000 peritoneal MΦs in vitro after immunization with liposomal cysteine proteases after 4 h, 16 h, 24 h, 48 h and 72 h infection with L. donovani. C, NO production by infected MΦs after 4 h, 16 h, 24 h, 48 h and 72 h of in vitro infection. The results are mean ± S.E. of five individual hamster per group, representative of two independent experiments with similar results. Statistically significant (*, p<0.01; **, p<0.001;***, p<0.0001) differences in MΦ infection, parasite multiplication and nitrite production were compared to PBS controls. Asterisks over line indicate significant differences between groups.