Table 2. Association among DKK1 level, β-catenin accumulation and clinicopathological factors in 63 patients with chondrosarcomas.
Clinicopathological Factors | Total No. of cases | DKK1 Level | P-value | β-catenin accumulation | P-value | ||
Low | High | Negative | Positive | ||||
Gender | 1.000 | 0.610 | |||||
Male | 36 | 15 | 21 | 18 | 18 | ||
Female | 27 | 11 | 16 | 11 | 16 | ||
Age(years) | 0.362 | 0.769 | |||||
≥40 | 49 | 22 | 27 | 22 | 27 | ||
<40 | 14 | 4 | 10 | 7 | 7 | ||
Anatomical Location | 0.279 | 1.000 | |||||
Limb bone | 21 | 11 | 10 | 10 | 11 | ||
Axial bone | 42 | 15 | 27 | 19 | 23 | ||
Histological Grade | 0.035* | 0.037* | |||||
Well-differentiated (I) | 32 | 18 | 14 | 19 | 13 | ||
Moderate (II) | 19 | 6 | 13 | 8 | 11 | ||
Poorly (III) | 12 | 2 | 10 | 2 | 10 | ||
MSTS stage | 0.020* | 0.011* | |||||
I A + I B | 34 | 19 | 15 | 21 | 13 | ||
II A+ II B | 29 | 7 | 22 | 8 | 21 | ||
β-catenin accumulation | 0.000* | ||||||
Negative | 29 | 20 | 9 | ||||
Positive | 34 | 6 | 28 |
P values recorded are the results from Chi-square Tests or Fisher’s Exact Tests. *P<0.05.