Table 3. Golgi disruption properties of the four hit compounds and reference compounds derived from HCI-based analysis of HeLa-G cells.

Compound	EC50 (µM)	GC50 (µM)	GC50/EC50	%GNL
C795-0925	14.4	36.9	2.6	63.4
D011-2120	61.5	38.2	0.6	16.4
F694-1532	20.0	35.3	1.8	19.5
G202-0362	13.6	23.7	1.7	61.2
Ribavirin	27.2	ND	>16	87.2
IFN-α2b	5.9 U/mL	9.9 U/mL	1.7	91.2

GC₅₀, effective concentration of compound that disrupts 50% of the Golgi complexes.

% GN_L, which is the lowest % of Golgi number achievable at the compound's highest concentration.

ND, not determined.