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. 2014 Aug 21;9(8):e105690. doi: 10.1371/journal.pone.0105690

Table 1. P. falciparum K13-propeller amino acid and nucleotide substitutions observed in Tororo, Uganda.

Codon Propellerblade Type Referenceaminoacid Mutantaminoacid NucleotideLocus Referenceallele Mutantallele n/N
189a - NS K T 566 A C 10/29
189a - NS K N 567 A T 1/29
334 - NS F L 1000 T C 2/102
368a - Syn L L 1104 A G 1/101c
439 - Syn F F 1317 T C 1/129
465 1 NS I T 1394 T C 1/129
467 1 Syn Q Q 1401 A G 1/131
522 2 Syn S Sb 1566 T C 1/132
558 3 NS Y H 1672 T C 1/133
578a 4 NS A S 1732 G T 1/133
617 5 NS A T 1849 G A 1/133
619 5 NS L S 1856 T C 1/133c
637 5 NS V Db 1910 T A 1/132

All data are relative to reference sequence PF3D7_1343700.

n = number of samples containing mutant allele.

N = number of samples sequenced at locus.

a

SNP has been previously identified (MalariaGen).

b

Different SNP in same codon has been previously reported (MalariaGen).

c

Polymorphism identified in mixed P. falciparum/P. ovale infection.