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. 2014 Aug 21;10(8):e1004322. doi: 10.1371/journal.ppat.1004322

Table 3. Summary of fold increase in CD8+ T cell recognition of EBV-antigens presented by shBNLF2a-LCLs compared to shControl-LCLs.

Fold increase
Expression phase of target antigen Target antigen Epitope HLA restriction Number of experiments* Range Median
IE BRLF1 YVL A2 11 6.5–30.7 17
IE BZLF1 DPY B7 4 7–14 8.3
E BMLF1 GLC A2 10 7–24 11.5
E BMRF1 TLD A2 5 7.5–12 9
E BNLF2b RPG B7 4 4.1–7 5.5
L BALF4 FLD A2 11 2–5 2.3
L BNRF1 WQW A2 4 2.3–3 2.5
L BNRF1 YPR B7 4 2–3.5 2.5

* more than one effector clone specific for each epitope was used where possible. In total, seven different donor LCLs were used.