FIGURE 5.

V3-expressing ASMCs had reduced hyaluronan accumulation. A, hyaluronan accumulated in the cell layers and media of control or V3-expressing ASMCs cultured for 2 weeks and quantified by ELSA as described under “Materials and Methods.” #, p < 0.05 in Student's t test. B, relative copy numbers of Has1, Has2, and Has3 mRNA levels were determined from samples obtained from four independent transductions of LXSN control and V3-transduced ASMC lines cultured for 2 weeks by qPCR as described under “Materials and Methods.” #, p < 0.05 in Student's t test. Error bars, S.E.