Table 2.
Hepatic gene expression in African green monkeys fed different amounts of dietary cholesterol
| Gene | Lo-chol | Hi-chol | p value |
|---|---|---|---|
| SREBP2 | 1.03 ± 0.13 | 0.51 ± 0.13 | 0.02 |
| HMGCR | 1.07 ± 0.20 | 0.48 ± 0.15 | 0.05 |
| apoE | 1.06 ± 0.17 | 1.22 ± 0.24 | n.s |
| ABCA1 | 1.13 ± 0.31 | 1.76 ± 0.55 | n.s. |
| ABCG1 | 1.17 ± 0.31 | 3.93 ± 0.84 | 0.01 |
| SRB1 | 1.18 ± 0.29 | 0.72 ± 0.22 | n.s. |
| LDLr | 1.18 ± 0.29 | 3.38 ± 1.90 | n.s. |
| FAS | 1.15 ± 0.26 | 3.72 ± 1.81 | n.s |
| CD36 | 1.22 ± 0.23 | 1.47 ± 0.25 | n.s |
Gene expression was determined by quantitative real time PCR and results were normalized to GAPDH. Results were then normalized to the mean value for each gene in the Lo-chol group, which was set to a value of 1. Mean ± SEM, n=5 per diet group.