Table 1.
PTP type | Approved symbol (based on HUGO gene Nomenclature Committee) | |
---|---|---|
1 | Class I Cys-based PTPs | |
Classical PTP’s | ||
Transmembrane receptor-like PTPs | PTPRA; PTPRB; PTPRC; PTPRD; PTPRE; PTPRF; PTPRG; PTPRH; PTPRJ; PTPRK; PTPRM; PTPRN2; PTPRO; PTPRQ; PTPRR; PTPRS; PTPRT; PTPRU; PTPRVP. |
|
Non-receptor PTPs | PTPN1; PTPN2; PTPN3; PTPN6; PTPN7; PTPN9; PTPN11; PTPN12; PTPN13; PTPN14; PTPN18; PTPN20A; PTPN20B; PTPN21; PTPN22; PTPN23. |
|
Dual specificity phosphatases | ||
MAP kinase phosphatases | DUSP1; DUSP2; DUSP4; DUSP5; DUSP6; DUSP7; DUSP8; DUSP9; DUSP10; STYXL1. |
|
Atypical dual specificity phosphatases | DUPD1; DUSP3; DUSP11; DUSP12; DUSP13; DUSP14; DUSP15; DUSP18; DUSP19; DUSP21; DUSP22; DUSP23; DUSP26; DUSP28; EPM2A; PTPMT1; RNGTT; STYX. |
|
Slingshots | SSH1; SSH2; SSH3. | |
PRLs | PTP4A1; PTP4A2; PTP4A3 | |
CDC14s | CDC14A; CDC14B; PTPDC1. | |
PTENs | PTEN; TENC1; TNS1. | |
Myotubularins | MTM1; MTMR1; MTMR2; MTMR3; MTMR4; SBF1; MTMR6; MTMR7; MTMR8; MTMR9; MTMR10; MTMR11; MTMR12; SBF2; MTMR14. |
|
2. | Class II Cys-based PTPs | ACP1 (Low molecular weight acid phosphatase) |
3. | Class III Cys-based PTPs | CDC25A; CDC25B; CDC25C. |
4. | Asp-based PTPs | EYA1; EYA2; EYA3; EYA4. |
5. | His-based PTPs | PAcP. |
Individual PTPs were classified and their expression in human prostate tissues were checked respectively in http://www.genenames.org and http://biogps.org and based on the published literature [2–5].
Abbreviations: DSPs, dual specificity phosphatases; MTMs, myotubularins; PAcP, prostatic acid phosphatase; PRLs, phosphatase of regenerating liver; PTEN, phosphatase and tensin homolog; PTP, protein tyrosine phosphatase; PTPR, protein tyrosine phosphatase, transmembrane receptor-type.