Table 1. Summary of cardiac anomalies of P1 Nkx2-5+/R52G mice (129/Sv background) (n=17).
| mouse ID |
phenotype (excluded atrial septal defect and ventricular noncompaction) |
tricuspid valve anomalies |
|---|---|---|
| 1 | - | incomplete delamination |
| 2 | VSD (perimembranous) | - |
| 3 | VSD (perimembranous) | - |
| 4 | VSD (perimembranous) | incomplete delamination |
| 5 | VSD (muscular) | incomplete delamination |
| 6 | multiple VSDs (perimembranous + muscular) | incomplete delamination |
| 7 | multiple VSDs (perimembranous + muscular) | - |
| 8 | multiple VSDs (perimembranous + muscular | - |
| 9 | multiple VSDs (perimembranous + muscular) | incomplete delamination |
| 10 | multiple VSDs (muscular) | - |
| 11 | multiple VSDs (muscular) | - |
| 12 | atrioventricular septal defect multiple VSDs (muscular) |
hypoplastic |
| 13 | atrioventricular septal defect double outlet right ventricle multiple VSDs (muscular) |
hypoplastic |
| 14 | atrioventricular septal defect double-chambered right ventricle right isomerism |
hypoplastic |
| 15 | Ebstein’s malformation | incomplete delamination,
Ebstein’s malformation |
| 16 | Ebstein’s malformation multiple VSDs (muscular) |
tethered, Ebstein’s malformation |
| 17 | tricuspid valve atresia small right ventricular cavity VSD (muscular) |
atresia |