. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Apr 13;1846(1):55–65. doi: 10.1016/j.bbcan.2014.04.003

Table-1.

Subsets of MDSCs in human cancers

Melanoma

	Lin⁻ HLA-DR⁻ CD33⁺	[19]

	CD15⁺ IL4Rα⁺	[21]
	CD14⁺ IL4Rα⁺

		[135]
	CD14⁺ HLA-DR^−/low	[136]
		[137]

	CD14⁺ HLA-DR^−/low Stat^high CD80⁺	[136]
	CD83⁺ DC-Sign⁺

	CD14⁺ HLA-DR^−/low	[135]

	CD11b⁺ HLA-DR⁻ Lin⁻	[138]
	CD14⁺ HLA-DR⁻ Lin⁻
	CD33⁺ HLA-DR⁻ Lin⁻
	CD15⁺ HLA-DR⁻ Lin⁻

Breast Cancer

	Lin⁻ HLA-DR⁻	[19]

	Lin^−/low HLA-DR⁻ CD33⁺ CD11b⁺	[137]

	CD15⁺ granulocytes	[139]
	CD15⁺ FSC^low SSC^high

Central Nervous System cancers

Neuroblastoma	CD11b⁺ CD33⁺ HLA-DR⁻	[140]

Glioblastoma	CD14⁺ CD33⁺ HLA-DR^−/low	[141]
Glioblastoma	CD15⁺ CD33⁺ HLA-DR⁻

Head and Neck Squamous Cell	Lin⁻ HLA-DR⁻	[19]

	CD11b⁺ CD14⁻ CD33⁺	[142]

	CD14⁺	[125]

	SSC^high CD66b⁺	[143]

Lung

NSCLC	CD11b⁺ CD14⁻ CD15⁺ CD33⁺	[144]

Lung Cancer	Lin⁻ HLA-DR⁻	[19]

	CD11b⁺ CD33⁺	[145]

	SSC^high CD66b⁺	[143]

Gastrointestinal Cancers

Hepatocellular carcinoma	CD14⁺ HLA-DR^−/low	[146]

Gastrointestinal	CD15⁺ CD14⁺ CD11b⁺ CD33⁺	[87]
Cancer	HLA-DR⁻

Colon	CD15⁺ IL4Rα⁺	[21]
Colon	CD14⁺ IL4Rα⁺

	CD15⁺ granulocytes	[139]
	CD15⁺ FSC^low SSC^high

	CD14⁺ HLA-DR^−/low S100A9⁺	[147]

Pancreas	CD15⁺ granulocytes	[139]
	CD45⁺ Lin⁻ CD33⁺ CD11b⁺ CD15⁺	[148]

Renal Cancers

	CD14⁺ IL-4Rα⁺	[149]
	CD15⁺ IL-4Rα⁺
	CD14⁺ HLA-DR^−/low
	CD11b⁺ CD14⁻ CD15⁺
	CD15⁺ FSC^low SSC^high
	Lin⁻ HLA-DR⁻ CD33⁺

	Lin⁻ HLA-DR⁻ CD33⁺	[150]
	Lin⁻ HLA-DR⁻ CD33⁺	[151]

	CD33⁺ HLA-DR⁻	[152]
	CD15⁺ CD14⁻

		[153]
	CD11b⁺ CD14⁻ CD15⁺	[154]
		[155]

	CD14⁺ HLA-DR^−/low	[156]

	CD14⁺ HLA-DR^−/low	[155]

Genitourinary Malignancies

Prostate	CD14⁺ HLA-DR^−/low	[20]

Bladder & Uretheral	SSC^high CD66b⁺	[143]
Ovarian	CD11b⁺ CD14⁺ CD15⁺ CD33⁺	[123]
Ovarian	HLA-DR^low CD33⁺ CD80⁻ CD83⁻

Abbreviations: SSC: side scatter FSC: forward scatter Lin: lineage DC-Sign: Ctype lectin highly expressed on dendritic cell