Table 3.
Mixed models (repeated measures) to predict MMSE and CDRSB decline and multiple regression model for Braak Stage
Baseline Variable |
MMSE* | CDRSB* | Braak Stage* |
---|---|---|---|
Age at Diagnosis |
0.14 (0.0006) | −0.008 (0.70) | −0.02 (0.01) |
Education | −0.17 (0.19) | 0.22 (0.004) | −0.043 (0.22) |
Gender (Male) | 0.29 (0.70) | −0.02 (0.97) | 0.09 (.31) |
APOE | 0.56 (0.27) | −0.29 (0.32) | |
Initial MMSE | .37 (0.001) | ||
Digit Backwards trials correct |
0.67 (0.004) | −0.29 (0.03) | |
Boston Naming Test |
0.23 (0.007) | ||
Initial CDR SB | 0.80 (<0.0001) | ||
Digit backwards length |
−0.15 (0.05) | ||
1st Behavioral Symptom |
0.76 (0.059) |
Beta (p – value). Interactions were explored and were non-significant.