Skip to main content
. Author manuscript; available in PMC: 2015 Sep 30.
Published in final edited form as: J Comput Chem. 2014 Jul 22;35(25):1824–1834. doi: 10.1002/jcc.23690

Figure 5.

Figure 5

The distribution of the area under the curve (AUC) of the receiver operating characteristic (ROC) curves of various shape-based virtual screening algorithms when applied to all 102 targets in the DUD-E benchmark. An AUC of 0.5 indicates random performance while an AUC of 1.0 indicates a perfect ranking of active ligands. Violin plots show the median value (dot), the range between the first and third quartile (solid block line), and the kernel density from the minimum to maximum values (shaded area).