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CD16.NK-92 cytolytic effectors induced ADCC mediated by parental CNTO 95 (A) and Herceptin (B) against melanoma A375 (black squares) and breast cancer SKBR3 (open circles) cells. Increasing concentrations of CNTO 95 or Herceptin antibodies were tested to trigger cytolytic activity by CD16.NK-92 toward the two different cancer cell lines. E:T ratio was 5:1. Data represent mean ± SD from four independent experiments with each condition tested in triplicates in each experiment.
