Figure 4.
Specific lysis of SKVO3 tumor cells by CD16.NK-92 induced by CNTO 95LF antibodies. The 51Cr-labeled SKVO3 tumor cells were incubated with CD16.NK-92 cells at E:T ratio 5:1 in the presence of CNTO 95LF (black circles) or CNTO 95 (open circles) or CNTO 95Ala-Ala (open diamonds) antibodies at indicated concentrations. In control experiments, normal human IgG (open squares) were also added (50 μg/ml) along with CNTO 95LF. The data shown are representative from five independent experiments with each antibody concentration tested in triplicates and depicted as mean ± SD. No significant difference by two-tailed Student t-test.