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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Neurochem. 2014 May 24;130(5):657–667. doi: 10.1111/jnc.12758

Figure 1. CK2 inhibition restores the excitatory effect of apamin on the firing activity of spinally projecting PVN neurons in SHRs.

Figure 1

A, Original traces show gramicidin perforated recordings of the firing activity of labeled PVN neurons before and during application of 100 nM apamin in WKY rat brain slices and SHR brain slices treated with DRB (100 μM, 2-4 h) or vehicle (0.1% dimethyl sulfoxide). B, Summary data show the effects of apamin on the firing activity in labeled PVN neurons in WKY rat brain slices and SHR brain slices treated with DRB or vehicle. Data are presented as means ± SEM *P < 0.05, compared with the respective baseline control (repeated measures ANOVA with Dunnett's post-hoc test).